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OPK OPKO Health, Inc.

USHealthcare
$1.35-2.53%ClosedMarket Cap: $1.02B

As of 2026-07-10 16:00

Why OPK matters now

OPKO Health, Inc. (OPK) is a US stock in Healthcare. The latest InvestLog snapshot shows $1.35 with -2.53% on the session and $1.02B in market capitalization; recent performance reads 1-month +23.48% and YTD +12.70%.

The latest financial table shown here is Q1 2026, with revenue of $124.2M, net income of $-54.8M, and EPS of $-0.07. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -16.2%.

The latest indexable market news headline is "Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026" from GlobeNewsWire.

Additional event context on this page matters because analyst consensus is Hold with a median target of $3.00; recent insider activity includes PAGANELLI JOHN A filing P-Purchase. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

0.89

P/S

1.85

EV/EBITDA

-32.49

DCF Value

$0.19

FCF Yield

-16.2%

Div Yield

0.0%

Margins & Returns

Gross Margin

22.7%

Operating Margin

-34.9%

Net Margin

-36.6%

ROE

-16.8%

ROA

-11.5%

ROIC

-10.9%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$124.2M$-54.8M$-0.07
Q4 2025$148.4M$-31.3M$-0.04
FY 2025$606.9M$-225.7M$-0.30
Q3 2025$151.7M$21.6M$0.03

Analyst Ratings

Consensus

Hold

Target (Consensus)

$2.87

Target (Median)

$3.00

Target Range

$1.60 - $4.00

Strong Buy: 2Buy: 2Hold: 3Sell: 0Strong Sell: 0
Barrington ResearchMarket Perform
2026-04-29
Barrington ResearchOutperform
2026-03-02
JefferiesHold
2025-10-31
Barrington ResearchOutperform
2025-10-30

Trading Activity

Insider Trades

PAGANELLI JOHN Adirector
Buy2026-03-20
UPPALURI SUBBARAO Vdirector
Sell2026-03-20
UPPALURI SUBBARAO Vdirector
Sell2026-03-20
UPPALURI SUBBARAO Vdirector
Sell2026-03-20
UPPALURI SUBBARAO Vdirector
Sell2026-03-20

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

1.49

OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.