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XNCR Xencor, Inc.

USHealthcare
$15.85-1.64%ClosedMarket Cap: $1.18B

As of 2026-07-10 16:00

Why XNCR matters now

Xencor, Inc. (XNCR) is a US stock in Healthcare. The latest InvestLog snapshot shows $15.85 with -1.64% on the session and $1.18B in market capitalization; recent performance reads 1-month +21.42% and YTD -17.44%.

The latest financial table shown here is Q1 2026, with revenue of $4.5M, net income of $-128.9M, and EPS of $-1.71. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -20.2%.

The latest indexable market news headline is "The Biology Came First." from GuruFocus.

Additional event context on this page matters because analyst consensus is Buy with a median target of $31.00; recent insider activity includes Montgomery Alan Bruce filing S-Sale. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

1.84

P/S

9.63

EV/EBITDA

-8.34

DCF Value

$-6.35

FCF Yield

-20.2%

Div Yield

0.0%

Margins & Returns

Gross Margin

36.2%

Operating Margin

-217.9%

Net Margin

-177.1%

ROE

-28.8%

ROA

-23.4%

ROIC

-30.6%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$4.5M$-128.9M$-1.71
Q4 2025$28.2M$-6.7M$-0.09
FY 2025$125.6M$-91.9M$-1.24
Q3 2025$21.0M$-6.0M$-0.08

Analyst Ratings

Consensus

Buy

Target (Consensus)

$35.30

Target (Median)

$31.00

Target Range

$18.00 - $58.00

Strong Buy: 3Buy: 9Hold: 2Sell: 0Strong Sell: 0
JP MorganNeutral
2026-05-11
JP MorganNeutral
2026-03-24
BarclaysOverweight
2026-02-26
BarclaysOverweight
2025-12-17
RBC CapitalOutperform
2025-11-06

Trading Activity

Insider Trades

Montgomery Alan Brucedirector
Sell2026-06-17
RANIERI RICHARD Jdirector
Sell2026-06-17
GUSTAFSON KURT Adirector
Sell2026-06-17
GORMAN KEVIN CHARLESdirector
Sell2026-06-17
Cornelissen Bart Janofficer: SR. VICE PRESIDENT & CFO
Sell2026-04-13

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

0.93

Xencor Inc., a biopharmaceutical firm headquartered in Monrovia, California, and established in 1997, operates as a clinical-stage entity. Its central mission involves the discovery and sophisticated engineering of monoclonal antibody and cytokine therapeutics, primarily aimed at treating patients afflicted with cancer and autoimmune disorders. The company is associated with several notable therapies currently in use, such as Sotrovimab, which targets the SARS-CoV-2 virus; Ultomiris, prescribed for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome; and Monjuvi, indicated for individuals with relapsed or refractory diffuse large B-cell lymphoma. Xencor maintains a robust and diverse pipeline of drug candidates advancing through various clinical trial stages. In oncology, this includes Plamotamab, a tumor-targeted antibody, currently undergoing Phase I trials for non-Hodgkin lymphoma; Vudalimab, a bispecific antibody in Phase II for metastatic castration-resistant prostate cancer and other solid tumor types; and Tidutamab, also in Phase II for neuroendocrine tumors. Further cancer-focused programs comprise XmAb306, XmAb104, and XmAb841, all in Phase I for selected solid tumors; AMG 509, in Phase I for prostate cancer; XmAb819, being developed for renal cell carcinoma; and a program involving Novartis XmAb. In the infectious disease arena, Xencor is progressing VIR-3434 through Phase II for hepatitis B virus infection; VIR-2482 in Phase 1/2 for influenza A; VIR-7832 in a Phase 1b/2a trial for mild-to-moderate COVID-19; and is involved in the Phase 2/3 NIH ACTIV-2 trial for COVID-19 with BMS-986414 + BMS-986413. Beyond these, the company is developing XmAb564, a Phase I candidate for autoimmune diseases; Obexelimab, also for autoimmune conditions; AIMab7195, designed to reduce IgE levels for allergic responses; and Xpro1595, an experimental treatment for Alzheimer's disease, mild cognitive impairment, and depression. Xencor also holds a licensing agreement with Caris Life Sciences.