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AXSM

Axsome Therapeutics, Inc.NASDAQHealthcare
$168.50-1.91%ClosedMarket Cap: $8.62B

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

96.63

P/S

13.50

EV/EBITDA

-51.28

DCF Value

$-563.05

FCF Yield

-1.1%

Div Yield

0.0%

Margins & Returns

Gross Margin

92.6%

Operating Margin

-26.5%

Net Margin

-28.7%

ROE

-254.1%

ROA

-28.7%

ROIC

-44.0%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$196.0M$-28.6M$-0.56
FY 2025$638.5M$-183.2M$-3.68
Q3 2025$171.0M$-47.2M$-0.94
Q2 2025$150.0M$-48.0M$-0.97

Analyst Ratings

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GuggenheimBuy
2026-03-25
UBSBuy
2026-02-24
RBC CapitalOutperform
2026-02-24
Wells FargoOverweight
2026-02-24
NeedhamBuy
2026-02-23

Trading Activity

Insider Trades

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TABUTEAU HERRIOTdirector, 10 percent owner, officer: Chief Executive Officer
SellFri Feb 27
Pizzie Nickofficer: Chief Financial Officer
SellFri Feb 27
Murdock Hunter R.officer: General Counsel
SellFri Feb 27
Maizel Ariofficer: Chief Commercial Officer
SellFri Feb 27
Jacobson Mark L.officer: Chief Operating Officer
SellFri Feb 27

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

0.47

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

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