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ARWR Arrowhead Pharmaceuticals, Inc.

USHealthcare
$60.74-1.20%ClosedMarket Cap: $8.56B

As of 2026-10-08

Why ARWR matters now

Arrowhead Pharmaceuticals, Inc. (ARWR) is a US stock in Healthcare. The latest InvestLog snapshot shows $60.74 with -1.20% on the session and $8.56B in market capitalization; recent performance reads 1-month +11.81% and YTD +23.24%.

The latest financial table shown here is Q2 2026, with revenue of $73.7M, net income of $-132.7M, and EPS of $-0.93. Investors can compare that operating picture with valuation signals such as P/E 45.10 and FCF yield -0.4%.

The latest indexable market news headline is "Arrowhead Pharmaceuticals (NASDAQ:ARWR) Stock Price Breaks Below 200 Day Moving Average – Here’s Why" from Defense World.

Additional event context on this page matters because analyst consensus is Buy with a median target of $95.00; recent insider activity includes Cohen Matthew Gregory filing . These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

45.10

PEG

0.34

P/B

18.98

P/S

18.53

EV/EBITDA

-94.52

DCF Value

$-99.57

FCF Yield

-0.4%

Div Yield

0.0%

Margins & Returns

Gross Margin

100.0%

Operating Margin

-35.7%

Net Margin

-48.4%

ROE

-55.4%

ROA

-13.3%

ROIC

-11.0%

Financials

PeriodRevenueNet IncomeEPS
Q2 2026$73.7M$-132.7M$-0.93
Q1 2026$264.0M$30.8M$0.22
Q4 2025$256.5M$-23.8M$-0.17
FY 2025$829.4M$-1.6M$-0.01

Analyst Ratings

Consensus

Buy

Target (Consensus)

$84.00

Target (Median)

$95.00

Target Range

$35.00 - $110.00

Strong Buy: 4Buy: 7Hold: 2Sell: 0Strong Sell: 0
Leerink PartnersMarket Perform
2026-06-17
BernsteinMarket Perform
2026-05-13
RBC CapitalOutperform
2026-05-08
Morgan StanleyOverweight
2026-04-21
HC Wainwright & Co.Buy
2026-03-25

Trading Activity

Insider Trades

Cohen Matthew Gregorydirector
Sell2026-06-17
Cohen Matthew Gregorydirector
Sell2026-06-17
Lu Hongbodirector
Sell2026-05-14
Hamilton James Cofficer: Chief Medical Officer
Sell2026-04-24
Apel Daniel Josephofficer: Chief Financial Officer
Sell2026-04-24

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

—

Beta

1.27

Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.