SYRE Spyre Therapeutics, Inc. logo

SYRE Spyre Therapeutics, Inc.

Healthcare
$73.65-0.54%ClosedMarket Cap: $4.45B

As of 2026-05-26

Valuation

P/E (TTM)

PEG

P/B

38.20

P/S

49.43

EV/EBITDA

-21.74

DCF Value

$0.23

FCF Yield

-4.2%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

-256.0%

Net Margin

-198.3%

ROE

-31.2%

ROA

-23.5%

ROIC

-34.1%

Income Statement

Periods shown are fiscal year quarters (may differ from calendar year)

PeriodRevenueGross MarginOperating IncomeNet IncomeEPSDividend
Q1 null$0.00NaN%$-75.6M$-69.0M$
Q4 null$90.5M50.0%$-57.2M$-62.5M$
FY null$0.00-Infinity%$-209.6M$-155.2M$
Q3 null$0.00-Infinity%$-56.9M$-11.2M$
Q2 null$0.00NaN%$-41.9M$-36.7M$
Q1 null$0.00NaN%$-53.6M$-44.8M$
Q4 null$0.00NaN%$-61.3M$-56.3M$
FY null$0.00NaN%$-208.6M$-208.0M$
Q3 null$0.00NaN%$-55.4M$-69.0M$
Q2 null$0.00NaN%$-44.1M$-38.8M$
Q1 null$0.00NaN%$-47.8M$-43.9M$
Q4 2023$0.00NaN%$-45.9M$-63.2M$-2.91