SPRO Spero Therapeutics, Inc.
HealthcareAs of 2026-05-25
Valuation
View DetailsP/E (TTM)
18.03
PEG
0.16
P/B
2.99
P/S
2.92
EV/EBITDA
7.52
DCF Value
$-30.48
FCF Yield
4.5%
Div Yield
0.0%
Margins & Returns
Gross Margin
100.0%
Operating Margin
24.7%
Net Margin
27.8%
ROE
35.6%
ROA
25.8%
ROIC
23.9%
Financials
View All| Period | Revenue | Net Income | EPS |
|---|---|---|---|
| Q1 null | $258.0K | $-7.2M | $— |
| Q4 null | $39.7M | $31.5M | $— |
| FY null | $59.6M | $8.6M | $— |
| Q3 null | $3.0M | $-7.4M | $— |
Analyst Ratings
View AllConsensus
Hold
Target (Consensus)
$—
Target (Median)
$—
Target Range
$— - $—
Trading Activity
Insider Trades
View AllCompany Info
Sector
Healthcare
Industry
Biotechnology
Country
US
Exchange
—
Beta
1.43
Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adults; SPR206, a direct acting IV-administered agent to treat MDR Gram-negative bacterial infections in the hospital; and SPR720, an oral antibiotic for the treatment of non-tuberculous mycobacterial pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; license agreement with Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; collaboration agreement with Bill & Melinda Gates Medical Research Institute to develop SPR720 for the treatment of lung infections caused by Mycobacterium tuberculosis; and license agreement with Vertex Pharmaceuticals Incorporated for patents relating to SPR720, as well as SPR719, an active metabolite. The company was founded in 2013 and is headquartered in Cambridge, Massachusetts.