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SNTI

Senti Biosciences, Inc.NASDAQHealthcare
$0.86+6.52%ClosedMarket Cap: $22.5M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

3.67

P/S

1089.99

EV/EBITDA

-0.63

DCF Value

$-0.07

FCF Yield

-182.0%

Div Yield

0.0%

Margins & Returns

Gross Margin

-14777.3%

Operating Margin

-289668.2%

Net Margin

-279263.6%

ROE

-322.4%

ROA

-119.9%

ROIC

-149.7%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$22.0K$-14.5M$-0.53
FY 2025$22.0K$-61.4M$-2.73
Q3 2025$0.00$-18.1M$-0.69
Q2 2025$0.00$-14.7M$-0.56

Analyst Ratings

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Chardan CapitalBuy
2026-03-30
Chardan CapitalBuy
2025-12-09
Chardan CapitalBuy
2025-08-08
Chardan CapitalBuy
2025-06-12
Chardan CapitalBuy
2025-05-02

Trading Activity

Insider Trades

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Rajangam Kanyaofficer: Pres. & Chief Med. & Dev. Off.
SellWed Mar 11
Lu Timothy Kdirector, officer: CEO
SellWed Mar 11
Rajangam Kanyaofficer: Pres. & Chief Med. & Dev. Off.
SellTue Feb 03
Lu Timothy Kdirector, officer: CEO
SellTue Feb 03
Baum Bryan Danieldirector
SellMon Jul 21

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

2.12

Senti Biosciences, Inc. operates as a gene circuit company. The company develops cell and gene therapies engineered with gene circuits that are designed to reprogram cells with biological logic to sense inputs, compute decisions, and respond to respective cellular environments. Its synthetic biology platform utilizes off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to target particularly challenging liquid and solid tumor oncology indications. The company's lead programs include SENTI-202, a Logic Gated OR+NOT off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells, while sparing the healthy bone marrow; and SENTI-301, a multi-armed off-the-shelf CAR-NK cell therapy designed for the treatment of hepatocellular carcinoma (HCC). It also develops SENTI-401, a Logic Gated (NOT) off-the-shelf CAR-NK cell therapy designed to target and eliminate colorectal cancer (CRC) cells, while sparing healthy cells in the body. The company was founded in 2016 and is based in South San Francisco, California.

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