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SNDX

Syndax Pharmaceuticals, Inc.NASDAQHealthcare
$25.15+5.32%ClosedMarket Cap: $2.22B

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

32.55

P/S

12.43

EV/EBITDA

-10.66

DCF Value

$15.48

FCF Yield

-15.1%

Div Yield

0.0%

Margins & Returns

Gross Margin

96.0%

Operating Margin

-158.4%

Net Margin

-165.6%

ROE

-206.6%

ROA

-53.9%

ROIC

-66.6%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$68.5M$-68.0M$-0.78
FY 2025$172.4M$-285.4M$-3.30
Q3 2025$45.9M$-60.7M$-0.70
Q2 2025$38.0M$-71.8M$-0.83

Analyst Ratings

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Goldman SachsBuy
2026-04-01
MizuhoOutperform
2026-03-31
JP MorganOverweight
2026-03-09
CitigroupBuy
2026-03-02
MizuhoOutperform
2026-01-27

Trading Activity

Insider Trades

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Metzger Michael Adirector, officer: Chief Executive Officer
SellTue Feb 10
Goldan Keith A.officer: Chief Financial Officer
SellTue Feb 10
Metzger Michael Adirector, officer: Chief Executive Officer
SellFri Feb 06
Metzger Michael Adirector, officer: Chief Executive Officer
SellFri Feb 06
Metzger Michael Adirector, officer: Chief Executive Officer
SellFri Feb 06

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

0.41

Syndax Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidates are SNDX-5613, which is in phase 1/2 clinical trial targeting the binding interaction of Menin with the mixed lineage leukemia 1 protein for the treatment of MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML); and SNDX-6352 or axatilimab, a monoclonal antibody that blocks the colony stimulating factor 1, or CSF-1 receptor for the treatment of patients with chronic graft versus host disease (cGVHD). The company is also developing Entinostat. It also has collaborative research and development agreement with National Cancer Institute; a clinical trial agreement with Eastern Cooperative Oncology Group; and a license agreement with Kyowa Hakko Kirin Co., Ltd. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in Waltham, Massachusetts.Massachusetts.

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