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SION Sionna Therapeutics, Inc.

USHealthcare
$44.94+2.14%ClosedMarket Cap: $2.03B

As of 2026-07-09 16:00

Why SION matters now

Sionna Therapeutics, Inc. (SION) is a US stock in Healthcare. The latest InvestLog snapshot shows $44.94 with +2.14% on the session and $2.03B in market capitalization; recent performance reads 1-month -1.01% and YTD -9.33%.

The latest financial table shown here is Q1 2026, with revenue of $0.00, net income of $-26.8M, and EPS of $-0.60. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -4.3%.

The latest indexable market news headline is "Sionna Therapeutics: NBD1 Stabilization Could Redefine Cystic Fibrosis Treatment" from Seeking Alpha.

Additional event context on this page matters because analyst consensus is Buy with a median target of $54.00; recent insider activity includes Booth Bruce filing A-Award. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

5.81

P/S

0.00

EV/EBITDA

-20.10

DCF Value

$1.23

FCF Yield

-4.3%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

0.0%

Net Margin

0.0%

ROE

-27.3%

ROA

-28.1%

ROIC

-33.4%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$0.00$-26.8M$-0.60
Q4 2025$0.00$-20.4M$-0.46
FY 2025$0.00$-75.3M$-1.88
Q3 2025$0.00$-20.3M$-0.46

Analyst Ratings

Consensus

Buy

Target (Consensus)

$54.00

Target (Median)

$54.00

Target Range

$50.00 - $58.00

Strong Buy: 1Buy: 8Hold: 1Sell: 0Strong Sell: 1
CitizensMarket Outperform
2026-05-26
Freedom BrokerHold
2026-05-20
StifelBuy
2026-05-18
BTIGBuy
2026-05-13
Jones TradingBuy
2026-04-28

Trading Activity

Insider Trades

Booth Brucedirector
Sell2026-06-18
Clancy Paul Jdirector
Sell2026-06-18
Fleming Harold Edwarddirector
Sell2026-06-18
Resnick Joshuadirector
Sell2026-06-18
Ruddy Marcella K.director
Sell2026-06-18

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

1.29

Operating as a biopharmaceutical company, Sionna Therapeutics, Inc. is dedicated to transforming the treatment landscape for individuals with cystic fibrosis. This is achieved by developing innovative medicines designed to restore the normal function of the cystic fibrosis transmembrane conductance regulator.