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PYXS Pyxis Oncology, Inc.

USHealthcare
$2.67+1.14%ClosedMarket Cap: $169.2M

As of 2026-07-10 16:00

Why PYXS matters now

Pyxis Oncology, Inc. (PYXS) is a US stock in Healthcare. The latest InvestLog snapshot shows $2.67 with +1.14% on the session and $169.2M in market capitalization; recent performance reads 1-month +6.28% and YTD +76.52%.

The latest financial table shown here is Q1 2026, with revenue of $0.00, net income of $-23.3M, and EPS of $-0.37. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -52.1%.

The latest indexable market news headline is "Pyxis Oncology Announces Up to $114 Million Private Placement Financing to Advance MICVO Through Key Clinical Milestones" from GlobeNewsWire.

Additional event context on this page matters because analyst consensus is Buy with a median target of $6.00; recent insider activity includes Palani Santhosh filing A-Award. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

4.12

P/S

9.28

EV/EBITDA

-1.84

DCF Value

$1.74

FCF Yield

-52.1%

Div Yield

0.0%

Margins & Returns

Gross Margin

99.8%

Operating Margin

-619.6%

Net Margin

-589.8%

ROE

-135.6%

ROA

-127.1%

ROIC

-173.4%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$0.00$-23.3M$-0.37
Q4 2025$11.0M$-18.1M$-0.29
FY 2025$13.9M$-79.6M$-1.28
Q3 2025$0.00$-22.0M$-0.35

Analyst Ratings

Consensus

Buy

Target (Consensus)

$6.00

Target (Median)

$6.00

Target Range

$6.00 - $6.00

Strong Buy: 1Buy: 8Hold: 1Sell: 0Strong Sell: 0
StifelBuy
2026-03-24
HC Wainwright & Co.Buy
2026-03-24
RBC CapitalOutperform
2025-12-19
HC Wainwright & Co.Buy
2025-12-19
Stephens & Co.Overweight
2025-11-24

Trading Activity

Insider Trades

Palani Santhoshdirector
Sell2026-03-25
HUMPHREY RACHELdirector
Sell2026-03-25
Cline Darren Sdirector
Sell2026-03-25
Lewis-Hall Freda Cdirector
Sell2026-03-25
Metzger Michael Adirector
Sell2026-03-25

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

1.43

Pyxis Oncology, Inc. operates as a preclinical biopharmaceutical company focused on developing novel therapeutic approaches to combat various forms of cancer. Its investigational immune-oncology pipeline includes PYX-106, a fully human immunoglobulin G1 (IgG1) antibody designed to target siglec-15, which is being explored for its potential efficacy against thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors. Additionally, PYX-102 is an immune-therapeutic currently under investigation for the treatment of solid tumors. The company's portfolio also features a range of investigational antibody-drug conjugate (ADC) candidates: PYX-201, a novel ADC being developed for NSCLC, breast cancer, and other solid tumors; PYX-202, another novel ADC aimed at small cell lung cancer (SCLC), soft tissue sarcoma, and other solid tumors; and PYX-203, an ADC undergoing evaluation for acute myeloid leukemia and myeloid dysplastic syndrome. Pyxis Oncology was founded in 2018 and is based in Cambridge, Massachusetts.