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PRTA Prothena Corporation plc

USHealthcare
$9.24-4.15%ClosedMarket Cap: $483.7M

As of 2026-07-10 16:00

Why PRTA matters now

Prothena Corporation plc (PRTA) is a US stock in Healthcare. The latest InvestLog snapshot shows $9.24 with -4.15% on the session and $483.7M in market capitalization; recent performance reads 1-month -1.54% and YTD -6.49%.

The latest financial table shown here is Q1 2026, with revenue of $51.1M, net income of $32.7M, and EPS of $0.60. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -17.4%.

The latest indexable market news headline is "PRTA Stock Rises Nearly 11% in Six Months: What's Driving It?" from Zacks Investment Research.

Additional event context on this page matters because analyst consensus is Hold with a median target of $19.00; recent insider activity includes SCULLY WILLIAM P filing P-Purchase. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

1.53

P/S

8.07

EV/EBITDA

-1.95

DCF Value

$3.52

FCF Yield

-17.4%

Div Yield

0.0%

Margins & Returns

Gross Margin

46.8%

Operating Margin

-217.9%

Net Margin

-260.9%

ROE

-49.9%

ROA

-43.2%

ROIC

-39.4%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$51.1M$32.7M$0.60
Q4 2025$21.0K$-21.6M$-0.40
FY 2025$9.7M$-244.1M$-4.53
Q3 2025$2.4M$-36.5M$-0.68

Analyst Ratings

Consensus

Hold

Target (Consensus)

$19.00

Target (Median)

$19.00

Target Range

$19.00 - $19.00

Strong Buy: 2Buy: 1Hold: 2Sell: 0Strong Sell: 1
CitizensMarket Outperform
2026-05-08
RBC CapitalSector Perform
2026-02-20
CitizensMarket Outperform
2025-12-01
HC Wainwright & Co.Buy
2025-11-07
RBC CapitalSector Perform
2025-11-07

Trading Activity

Insider Trades

SCULLY WILLIAM P10 percent owner
Buy2026-06-18
SCULLY WILLIAM P10 percent owner
Sell2026-06-16
SCULLY WILLIAM P10 percent owner
Buy2026-06-12
Isaacs Michael Johnofficer: General Counsel & Company Sec.
Sell2026-06-12
Isaacs Michael Johnofficer: General Counsel & Company Sec.
Sell2026-06-12

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

-0.32

Established in 2012 and headquartered in Dublin, Ireland, Prothena Corporation plc functions as a clinical-stage biopharmaceutical company focused on the discovery and advancement of novel therapeutic solutions for critical, life-threatening conditions, primarily within the United States. The company's pipeline features several key programs: Birtamimab, an investigational humanized antibody, is currently undergoing Phase III clinical trials for the treatment of AL amyloidosis. Prasinezumab, a humanized monoclonal antibody, is progressing through Phase IIb trials for Parkinson's disease. Prothena has also completed Phase I clinical trials for PRX004, indicated for Transthyretin amyloidosis, and is advancing PRX005 through Phase I for Alzheimer's disease. In its earlier-stage development, Prothena is exploring PRX012 for Alzheimer's disease, alongside a dual Aß-Tau vaccine designed for both the treatment and prevention of Alzheimer's disease. Prothena maintains strategic partnerships, including a comprehensive license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. for antibodies targeting alpha-synuclein. The company also collaborates with Bristol-Myers Squibb on antibody development.