PRTA Prothena Corporation plc logo

PRTA Prothena Corporation plc

Healthcare
$9.83+4.46%ClosedMarket Cap: $514.6M

As of 2026-05-25

Valuation

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P/E (TTM)

PEG

P/B

1.69

P/S

8.88

EV/EBITDA

-2.36

DCF Value

$3.52

FCF Yield

-15.8%

Div Yield

0.0%

Margins & Returns

Gross Margin

46.8%

Operating Margin

-217.9%

Net Margin

-260.9%

ROE

-49.9%

ROA

-43.2%

ROIC

-39.4%

Financials

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PeriodRevenueNet IncomeEPS
Q1 null$51.1M$32.7M$
Q4 null$21.0K$-21.6M$
FY null$9.7M$-244.1M$
Q3 null$2.4M$-36.5M$

Analyst Ratings

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Consensus

Hold

Target (Consensus)

$19.00

Target (Median)

$19.00

Target Range

$19.00 - $19.00

2 Strong Buy1 Buy2 Hold0 Sell1 Strong Sell
CitizensMarket Outperform
2026-05-08
RBC CapitalSector Perform
2026-02-20
CitizensMarket Outperform
2025-12-01
HC Wainwright & Co.Buy
2025-11-07
RBC CapitalSector Perform
2025-11-07

Trading Activity

Insider Trades

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WELCH DANIEL Gdirector
SellFri May 15
Selkoe Dennis J.director
SellFri May 15
Ekman Larsdirector
SellFri May 15
Dunn William H. Jr.director
SellFri May 15
Cooke Shanedirector
SellFri May 15

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

IE

Exchange

Beta

-0.23

Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.

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