PRLD Prelude Therapeutics Incorporated logo

PRLD Prelude Therapeutics Incorporated

Healthcare
$4.27-1.39%ClosedMarket Cap: $243.1M

As of 2026-05-25

Valuation

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P/E (TTM)

PEG

P/B

5.85

P/S

14.54

EV/EBITDA

-2.90

DCF Value

$3.63

FCF Yield

-18.0%

Div Yield

0.0%

Margins & Returns

Gross Margin

97.7%

Operating Margin

-503.2%

Net Margin

-465.3%

ROE

-118.2%

ROA

-65.0%

ROIC

-104.3%

Financials

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PeriodRevenueNet IncomeEPS
Q1 null$4.6M$-10.4M$
Q4 null$5.6M$-16.5M$
FY null$12.1M$-99.5M$
Q3 null$6.5M$-19.7M$

Analyst Ratings

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Consensus

Buy

Target (Consensus)

$8.00

Target (Median)

$8.00

Target Range

$8.00 - $8.00

1 Strong Buy3 Buy0 Hold0 Sell0 Strong Sell
HC Wainwright & Co.Buy
2026-04-27
CitizensMarket Outperform
2026-03-11
HC Wainwright & Co.Buy
2025-09-23
JMP SecuritiesMarket Outperform
2025-08-18

Trading Activity

Insider Trades

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Morris Charles Qofficer: Chief Medical Officer
SellMon May 04
RA CAPITAL MANAGEMENT, L.P.10 percent owner
SellTue Apr 28
RA CAPITAL MANAGEMENT, L.P.10 percent owner
SellTue Apr 28
ORBIMED ADVISORS LLCdirector, 10 percent owner:
BuyThu Apr 23
ORBIMED ADVISORS LLCdirector, 10 percent owner:
BuyThu Apr 23

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

1.10

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.

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