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PRLD Prelude Therapeutics Incorporated

USHealthcare
$6.47-2.41%ClosedMarket Cap: $368.4M

As of 2026-08-24

Why PRLD matters now

Prelude Therapeutics Incorporated (PRLD) is a US stock in Healthcare. The latest InvestLog snapshot shows $6.47 with -2.41% on the session and $368.4M in market capitalization; recent performance reads 1-month +1.17% and YTD +48.97%.

The latest financial table shown here is Q1 2026, with revenue of $4.6M, net income of $-10.4M, and EPS of $-0.13. Investors can compare that operating picture with valuation signals such as P/E unavailable and FCF yield -17.8%.

The latest indexable market news headline is "Wall Street Analysts See a 58.42% Upside in Prelude Therapeutics (PRLD): Can the Stock Really Move This High?" from Zacks Investment Research.

Additional event context on this page matters because analyst consensus is Buy with a median target of $8.00; recent insider activity includes FRIEDMAN PAUL A filing A-Award. These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

PEG

P/B

5.92

P/S

14.71

EV/EBITDA

-3.18

DCF Value

$3.87

FCF Yield

-17.8%

Div Yield

0.0%

Margins & Returns

Gross Margin

97.7%

Operating Margin

-503.2%

Net Margin

-465.3%

ROE

-118.2%

ROA

-65.0%

ROIC

-104.3%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$4.6M$-10.4M$-0.13
Q4 2025$5.6M$-16.5M$-0.26
FY 2025$12.1M$-99.5M$-1.29
Q3 2025$6.5M$-19.7M$-0.26

Analyst Ratings

Consensus

Buy

Target (Consensus)

$8.00

Target (Median)

$8.00

Target Range

$8.00 - $8.00

Strong Buy: 1Buy: 2Hold: 0Sell: 0Strong Sell: 0
HC Wainwright & Co.Buy
2026-04-27
CitizensMarket Outperform
2026-03-11
HC Wainwright & Co.Buy
2025-09-23
JMP SecuritiesMarket Outperform
2025-08-18

Trading Activity

Insider Trades

FRIEDMAN PAUL Adirector
Sell2026-06-10
Sandor Victordirector
Sell2026-06-10
Bonita David Pdirector, 10 percent owner:
Sell2026-06-10
Babler Martindirector
Sell2026-06-10
Dorton Katinadirector
Sell2026-06-10

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

1.01

Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on identifying and developing innovative, targeted cancer treatments for patient populations with unmet medical needs. Its pipeline includes PRT543, currently undergoing Phase 1 clinical evaluation for certain solid tumors and myeloid malignancies. Another asset, PRT811, is also in Phase 1 trials, targeting various solid tumors, notably glioblastoma multiforme. The company is additionally progressing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a powerful and highly kinome-selective CDK9 inhibitor; PRT-SCA2, which is in preclinical development for several genomically selected cancers; PRT3645, a brain-penetrant molecule that precisely and effectively targets CDK4/6; and PRT-K4, another preclinical compound for solid tumors. Founded in 2016, the firm's headquarters are located in Wilmington, Delaware.