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Prelude Therapeutics IncorporatedNASDAQHealthcare
$3.46+0.29%ClosedMarket Cap: $192.8M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

3.17

P/S

15.88

EV/EBITDA

-1.72

DCF Value

$4.49

FCF Yield

-29.2%

Div Yield

0.0%

Margins & Returns

Gross Margin

93.1%

Operating Margin

-861.3%

Net Margin

-819.6%

ROE

-130.0%

ROA

-70.4%

ROIC

-114.8%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$5.6M$-16.5M$-0.26
FY 2025$12.1M$-99.5M$-1.29
Q3 2025$6.5M$-19.7M$-0.26
Q2 2025$0.00$-31.2M$-0.41

Analyst Ratings

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CitizensMarket Outperform
2026-03-11
HC Wainwright & Co.Buy
2025-09-23
JMP SecuritiesMarket Outperform
2025-08-18
HC Wainwright & Co.Buy
2025-05-05
JMP SecuritiesMarket Outperform
2025-04-29

Trading Activity

Insider Trades

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Brusky Sean P.officer: Chief Business Officer
SellThu Mar 19
Brusky Sean P.officer: Chief Business Officer
SellThu Mar 19
Combs Andrewofficer: Chief Chemistry Officer
SellThu Feb 05
Scherle Peggyofficer: Chief Scientific Officer
SellThu Feb 05
Lim Bryant Davidofficer: CLO, CFO, Corp Sec.
SellThu Feb 05

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

0.71

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.

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