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NuCana plcNASDAQHealthcare
$1.63+3.07%ClosedMarket Cap: $9.9M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

0.19

P/S

0.00

EV/EBITDA

0.77

DCF Value

$8.80

FCF Yield

-95.8%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

0.0%

Net Margin

0.0%

ROE

-189.9%

ROA

-98.5%

ROIC

-70.2%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$0.00$-2.5M$-0.66
FY 2025$0.00$-28.7M$-7.75
Q3 2025$0.00$-281.0K$-0.08
Q2 2025$0.00$-24.1M$-4.00

Trading Activity

Insider Trades

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Levy Elliott M.director
SellWed Apr 01
Levy Elliott M.director
SellWed Apr 01
Levy Elliott M.director
SellWed Apr 01
Harrison David Jamesofficer: Head of Translational Medicine
SellTue Mar 24
Mellish Martin C.B.director
SellFri Mar 20

Company Info

Sector

Healthcare

Industry

Country

GB

Exchange

NASDAQ

Beta

1.80

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of products for the treatment of cancer. The company develops its products based on its proprietary ProTide technology. Its lead product candidate includes Acelarin, which is in Phase I clinical trial for patients with advanced solid tumors; Phase Ib for patients with recurrent ovarian cancer; Phase Ib clinical trials for the treatment of patients with biliary tract cancer; Phase II clinical trial for the treatment of patients with platinum-resistant ovarian cancer; and Phase III clinical trial for the treatment of patients with pancreatic cancer. The company is also developing NUC-3373, a ProTide transformation of the active anti-cancer metabolite of 5-fluorouracil, which is in Phase I clinical trial for the treatment of patients with advanced solid tumors and in a Phase 1b/2 clinical trial for patients with advanced colorectal cancer; and NUC-7738, a nucleoside analog that is in Phase 1/2 clinical trial for the treatment of patients with advanced solid tumors and hematological tumors. It has a research, collaboration, and license agreement with Cardiff University and University College Cardiff Consultants Ltd. for the design, synthesis, characterization, and evaluation of ProTides; and an assignment, license, and collaboration agreement with Cardiff ProTides Ltd. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is headquartered in Edinburgh, the United Kingdom.

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