LYRA logo

LYRA

Lyra Therapeutics, Inc.NASDAQHealthcare
$0.44-11.98%ClosedMarket Cap: $781,126

As of 2026-04-04

Valuation

View Details

P/E (TTM)

PEG

P/B

-0.64

P/S

1.96

EV/EBITDA

-0.49

DCF Value

$-2.81

FCF Yield

-3709.4%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

-7794.5%

Net Margin

-7266.1%

ROE

1211.1%

ROA

-80.1%

ROIC

-98.7%

Financials

View All
PeriodRevenueNet IncomeEPS
Q4 2025$7.0K$-7.0M$-9.60
FY 2025$398.0K$-28.9M$-18.62
Q3 2025$25.0K$-6.0M$-3.38
Q2 2025$183.0K$-7.4M$-5.51

Analyst Ratings

View All
HC Wainwright & Co.Neutral
2025-08-14
HC Wainwright & Co.Neutral
2025-06-10

Trading Activity

Insider Trades

View All
Cavalier Jasonofficer: Principal Financial Officer
SellFri Apr 03
Palasis Mariadirector, officer: Principal Executive Officer
SellFri Apr 03
Cavalier Jasonofficer: Chief Financial Officer
SellThu Jan 08
Palasis Mariadirector, officer: President & CEO
SellThu Jan 08
PERCEPTIVE ADVISORS LLC10 percent owner
SellThu Nov 13

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

0.06

Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical trial for the treatment of chronic rhinosinusitis (CRS); and LYR-220 for CRS patients who have failed previous medical management and continue to require treatment to manage CRS symptoms. It has a collaboration agreement with LianBio Inflammatory Limited to develop and commercialize LYR-210 in mainland China, Hong Kong, Taiwan, Macau, South Korea, Singapore, and Thailand. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.

Peers