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FULC

Fulcrum Therapeutics, Inc.NASDAQHealthcare
$8.04+7.49%ClosedMarket Cap: $435.1M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

1.42

P/S

0.00

EV/EBITDA

-3.05

DCF Value

$3.00

FCF Yield

-14.3%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

0.0%

Net Margin

0.0%

ROE

-30.2%

ROA

-20.4%

ROIC

-23.8%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$0.00$-20.3M$-0.31
FY 2025$0.00$-74.9M$-1.18
Q3 2025$0.00$-19.6M$-0.31
Q2 2025$0.00$-17.3M$-0.28

Analyst Ratings

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Truist SecuritiesBuy
2025-12-11
B of A SecuritiesUnderperform
2025-12-09
RBC CapitalSector Perform
2025-12-08
Cantor FitzgeraldOverweight
2025-12-08
Piper SandlerOverweight
2025-12-08

Trading Activity

Insider Trades

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Gould Robert Jdirector
SellWed Feb 04
Musso Alan Aofficer: Chief Financial Officer
SellWed Feb 04
Oltmans Curtis Galeofficer: Chief Legal Officer
SellWed Feb 04
Tourangeau Gregofficer: Principal Accounting Officer
SellWed Feb 04
Sapir Alexdirector, officer: See Remarks
SellWed Feb 04

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

3.27

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia. The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases. Fulcrum Therapeutics, Inc. has research and discovery collaboration agreement with Acceleron Pharma Inc. to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc. to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

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