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Cyclerion Therapeutics, Inc.NASDAQHealthcare
$6.15-3.61%ClosedMarket Cap: $23.4M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

1.47

P/S

7.62

EV/EBITDA

-2.52

DCF Value

$0.93

FCF Yield

-21.0%

Div Yield

0.0%

Margins & Returns

Gross Margin

100.0%

Operating Margin

-239.8%

Net Margin

-170.1%

ROE

-39.2%

ROA

-35.3%

ROIC

-54.7%

Financials

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PeriodRevenueNet IncomeEPS
Q3 2025$875.0K$-976.0K$-0.30
Q2 2025$93.0K$-324.0K$-0.11
Q1 2025$81.0K$-1.4M$-0.56
Q4 2024$1.8M$530.0K$0.21

Trading Activity

Insider Trades

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CHICKO RHONDA M.officer: Chief Financial Officer
SellMon Aug 11
Hecht Peter Mdirector, 10 percent owner:
SellThu Mar 27
Higgins Michael Jdirector
SellThu Mar 27
Slate Path Capital LP10 percent owner
SellMon Nov 25
Graul Regina Margaretdirector, officer: See Remarks
SellWed Aug 07

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

0.93

Cyclerion Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovering, development, and commercialization of medicines for serious central nervous system (CNS) diseases. Its lead product candidate is CY6463, a CNS-penetrant, soluble guanylate cyclase (sGC) stimulator that is in Phase IIa trials for the treatment of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes, as well as Alzheimer's disease with vascular pathology; and Phase 1 trials diagnosed with schizophrenia in adults. It is also developing Praliciguat, an orally administered systemic sGC stimulator, which is in Phase II studies to treat resistant hypertension and diabetic nephropathy; Olinciguat, an orally administered vascular sGC stimulator that is in Phase II studies for the sickle cell disease; and CY3018 for the treatment of disorders of the CNS. It has license agreement with Akebia Therapeutics, Inc. for the development, manufacture, medical affairs, and commercialization of pharmaceutical products, including pharmaceutical compound, and other related products and forms. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

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