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Alto Neuroscience, Inc.NYSEHealthcare
$21.68-7.39%ClosedMarket Cap: $692.6M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

4.76

P/S

0.00

EV/EBITDA

-9.20

DCF Value

$5.91

FCF Yield

-7.2%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

0.0%

Net Margin

0.0%

ROE

-48.2%

ROA

-34.2%

ROIC

-37.9%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$0.00$-16.2M$-0.51
FY 2025$0.00$-63.2M$-2.19
Q3 2025$0.00$-14.2M$-0.52
Q2 2025$0.00$-17.7M$-0.65

Analyst Ratings

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Chardan CapitalBuy
2026-04-02
BairdOutperform
2026-04-02
HC Wainwright & Co.Buy
2026-04-02
Jones TradingBuy
2026-04-02
WedbushNeutral
2026-04-02

Trading Activity

Insider Trades

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Etkin Amitdirector, officer: PRESIDENT AND CEO
SellTue Mar 03
Smith Nicholas Conradofficer: CHIEF FINANCIAL OFFICER & CBO
SellTue Mar 03
Etkin Amitdirector, officer: PRESIDENT AND CEO
SellFri Feb 13
Savitz Adamofficer: CHIEF MEDICAL OFFICER
SellFri Feb 13
Smith Nicholas Conradofficer: CHIEF FINANCIAL OFFICER & CBO
SellFri Feb 13

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NYSE

Beta

2.06

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company that engages in the psychiatry drug development business. The company develops ALTO-100 for the treatment of patients with major depressive disorder (MDD) and post-traumatic stress disorder; ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties to treat patients with MDD; and ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor for the treatment of cognitive impairment associated with schizophrenia. It also develops ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist to treat patients with MDD and higher levels of anhedonia, and ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor for the treatment of MDD. In addition, the company develops novel pharmacodynamically synergistic combinations and an AI-enabled biomarker platform that combine sources of information on patients brain activity and behavior to identify patients to respond to novel product candidates. Alto Neuroscience, Inc. was incorporated in 2019 and is based in Los Altos, California.

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