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Annexon, Inc.NASDAQHealthcare
$5.50+2.61%ClosedMarket Cap: $657.8M

As of 2026-04-06

Valuation

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P/E (TTM)

PEG

P/B

4.03

P/S

0.00

EV/EBITDA

-2.44

DCF Value

$0.79

FCF Yield

-28.4%

Div Yield

0.0%

Margins & Returns

Gross Margin

0.0%

Operating Margin

0.0%

Net Margin

0.0%

ROE

-101.3%

ROA

-74.5%

ROIC

-91.0%

Financials

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PeriodRevenueNet IncomeEPS
Q4 2025$0.00$-48.3M$-0.26
FY 2025$0.00$-206.7M$-1.34
Q3 2025$0.00$-54.9M$-0.37
Q2 2025$0.00$-49.2M$-0.34

Analyst Ratings

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Chardan CapitalBuy
2026-03-20
Wells FargoOverweight
2025-11-19
HC Wainwright & Co.Buy
2025-08-15
HC Wainwright & Co.Buy
2025-05-14
NeedhamBuy
2025-05-13

Trading Activity

Insider Trades

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Carson William H.director
BuyThu Mar 12
Dananberg Jamieofficer: CHIEF MEDICAL OFFICER
SellWed Mar 04
Overdorf Michaelofficer: EVP & CHIEF BUSINESS OFFICER
SellWed Mar 04
Yednock Tedofficer: EVP & CHIEF INNOVATION OFFICER
SellWed Mar 04
ARTIS DEAN RICHARDofficer: EVP & CHIEF SCIENTIFIC OFFICER
SellWed Mar 04

Company Info

Sector

Healthcare

Industry

Country

US

Exchange

NASDAQ

Beta

1.15

Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy. In addition, it develops ANX105, an investigational monoclonal antibody targeting neurodegenerative indications; and ANX1502, an investigational oral small molecule for the treatment of certain autoimmune indications. The company was incorporated in 2011 and is headquartered in Brisbane, California.

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