ALNY Alnylam Pharmaceuticals, Inc. logo

ALNY Alnylam Pharmaceuticals, Inc.

Healthcare
$297.45-1.02%ClosedMarket Cap: $39.71B

As of 2026-05-25

Valuation

View Details

P/E (TTM)

136.16

PEG

0.64

P/B

36.76

P/S

9.26

EV/EBITDA

64.01

DCF Value

$-1,714.43

FCF Yield

1.6%

Div Yield

0.0%

Margins & Returns

Gross Margin

80.9%

Operating Margin

17.5%

Net Margin

13.5%

ROE

98.3%

ROA

11.3%

ROIC

19.7%

Financials

View All
PeriodRevenueNet IncomeEPS
Q1 null$1.17B$206.0M$
Q4 null$1.10B$186.4M$
FY null$3.71B$313.7M$
Q3 null$1.25B$251.1M$

Analyst Ratings

View All

Consensus

Buy

Target (Consensus)

$445.67

Target (Median)

$445.50

Target Range

$351.00 - $530.00

7 Strong Buy15 Buy8 Hold0 Sell0 Strong Sell
HC Wainwright & Co.Buy
2026-05-05
RBC CapitalOutperform
2026-05-01
Wells FargoEqual Weight
2026-05-01
Truist SecuritiesBuy
2026-04-13
HC Wainwright & Co.Buy
2026-03-25

Trading Activity

Insider Trades

View All
Sigal Charles Elliottdirector
SellFri May 22
Sigal Charles Elliottdirector
SellFri May 22
SCHULMAN AMY Wdirector
SellFri May 22
SCHULMAN AMY Wdirector
SellFri May 22
Reitan Colleen Fdirector
SellFri May 22

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

0.30

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. The company's pipeline of investigational RNAi therapeutics focuses on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system (CNS)/ocular diseases. Its marketed products include ONPATTRO (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1 (PH1). In addition, the company is developing givosiran for the treatment of adolescent patients with AHP; patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; ALN-AAT02 for the treatment of AAT deficiency-associated liver disease; ALN-HBV02 to treat chronic HBV infection; Zilebesiran to treat hypertension; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia and rare bleeding disorders, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1 and recurrent renal stones, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Sanofi Genzyme to discover, develop, and commercialize RNAi therapeutics. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Peers