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ALNY Alnylam Pharmaceuticals, Inc.

USHealthcare
$323.50+0.59%ClosedMarket Cap: $43.19B

As of 2026-07-08 16:00

Why ALNY matters now

Alnylam Pharmaceuticals, Inc. (ALNY) is a US stock in Healthcare. The latest InvestLog snapshot shows $323.50 with +0.59% on the session and $43.19B in market capitalization; recent performance reads 1-month -5.51% and YTD -30.07%.

The latest financial table shown here is Q1 2026, with revenue of $1.17B, net income of $206.0M, and EPS of $1.51. Investors can compare that operating picture with valuation signals such as P/E 136.16 and FCF yield 1.7%.

The latest indexable market news headline is "Can Alnylam's Drug Pipeline Fuel Its Long-Term Revenue Growth?" from Zacks Investment Research.

Additional event context on this page matters because analyst consensus is Buy with a median target of $447.00; recent insider activity includes Cravatt Benjamin filing . These signals are research inputs, not a recommendation.

Valuation

P/E (TTM)

136.16

PEG

0.64

P/B

34.37

P/S

8.66

EV/EBITDA

39.69

DCF Value

$-1,780.45

FCF Yield

1.7%

Div Yield

0.0%

Margins & Returns

Gross Margin

80.9%

Operating Margin

17.5%

Net Margin

13.5%

ROE

98.3%

ROA

11.3%

ROIC

19.7%

Financials

PeriodRevenueNet IncomeEPS
Q1 2026$1.17B$206.0M$1.51
Q4 2025$1.10B$186.4M$1.37
FY 2025$3.71B$313.7M$2.33
Q3 2025$1.25B$251.1M$1.84

Analyst Ratings

Consensus

Buy

Target (Consensus)

$454.27

Target (Median)

$447.00

Target Range

$370.00 - $530.00

Strong Buy: 7Buy: 15Hold: 8Sell: 0Strong Sell: 0
HC Wainwright & Co.Buy
2026-06-04
RBC CapitalOutperform
2026-05-01
Wells FargoEqual Weight
2026-05-01
Truist SecuritiesBuy
2026-04-13
HC Wainwright & Co.Buy
2026-03-25

Trading Activity

Insider Trades

Cravatt Benjamindirector:
Sell2026-06-03
Cravatt Benjamindirector
Sell2026-06-03
PYOTT DAVID E Idirector
Sell2026-06-03
PYOTT DAVID E Idirector
Sell2026-06-03
PYOTT DAVID E Idirector
Sell2026-06-03

Company Info

Sector

Healthcare

Industry

Biotechnology

Country

US

Exchange

Beta

0.27

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.